|
KMID : 0388520140260020049
|
|
Nursing Science - Ewha Womans University
2014 Volume.26 No. 2 p.49 ~ p.64
|
|
|
Effects of Excercise on Immune Function in Patients with Cancer: A Systematic Review
|
|
Kwak So-Young
Kim Ji-In
Bae Jung-A
Jang Mi-Young
|
|
|
Abstract
|
|
|
Purpose: The purpose of this study was to systematically review changes in immune parameters after exercise in cancer patients.
Methods: The literature was identified through the Pubmed, CINAHL Plus, Cochran, Research Information Sharing Service (RISS), Koreanstudies Information Service System (KISS) and DataBase Periodical Information Academic (DBpia) between 2000 and 2014. Key words such as cancer, exercise and immune function were used.
Results: Twenty seven studies were included. Of the 27 included studies, 22 studies(81.48%) were identified as having significant effects of exercise on immune function. Aerobic exercise has been applied by 11 studies(40.74%) and eight studies(72.72%) of them reported changes in immune parameters after exercise. Immune parameters were divided into five categories (leukocyte types, lymphocyte subsets, immune cells functions, the soluble inflammatory mediators and immunoglobulin). 10 studies measured the effects of exercise on leukocyte types and four studies(40%) of them showed significant changes. Four studies investigated the Natural killer cell cytotoxic activity (NKCA) and all of them showed significant differences.
Conclusion: In this systematic review, we found that leukocyte counts and NKCA could be an effective parameter on immune function after exercise in cancer patients. This study has focussed on cancer patients, and therefore a future study will be needed to involve more various populations.
|
|
|
KEYWORD
|
|
|
Neoplasms, Exercise, Immune system
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|